diff --git a/test/pc/e2e/BUILD.gn b/test/pc/e2e/BUILD.gn
index 163e274f59..1b0e738596 100644
--- a/test/pc/e2e/BUILD.gn
+++ b/test/pc/e2e/BUILD.gn
@@ -490,6 +490,9 @@ if (!build_with_chromium) {
         "../../../test:test_support",
       ]
       data = peer_connection_e2e_smoke_test_resources
+      if (is_mac || is_ios) {
+        deps += [ "../../../modules/video_coding:objc_codec_factory_helper" ]
+      }
       if (is_ios) {
         deps += [ ":peer_connection_e2e_smoke_test_resources_bundle_data" ]
       }
diff --git a/test/pc/e2e/peer_connection_e2e_smoke_test.cc b/test/pc/e2e/peer_connection_e2e_smoke_test.cc
index f861d88a8e..09c40a6d75 100644
--- a/test/pc/e2e/peer_connection_e2e_smoke_test.cc
+++ b/test/pc/e2e/peer_connection_e2e_smoke_test.cc
@@ -27,6 +27,10 @@
 #include "test/pc/e2e/stats_based_network_quality_metrics_reporter.h"
 #include "test/testsupport/file_utils.h"
 
+#if defined(WEBRTC_MAC) || defined(WEBRTC_IOS)
+#include "modules/video_coding/codecs/test/objc_codec_factory_helper.h"  // nogncheck
+#endif
+
 namespace webrtc {
 namespace webrtc_pc_e2e {
 namespace {
@@ -183,6 +187,59 @@ TEST_F(PeerConnectionE2EQualityTestSmokeTest, MAYBE_Smoke) {
   RunAndCheckEachVideoStreamReceivedFrames(run_params);
 }
 
+#if defined(WEBRTC_MAC) || defined(WEBRTC_IOS)
+TEST_F(PeerConnectionE2EQualityTestSmokeTest, SmokeH264) {
+  std::pair<EmulatedNetworkManagerInterface*, EmulatedNetworkManagerInterface*>
+      network_links = CreateNetwork();
+
+  AddPeer(network_links.first, [](PeerConfigurer* alice) {
+    VideoConfig video(160, 120, 15);
+    video.stream_label = "alice-video";
+    video.sync_group = "alice-media";
+    alice->AddVideoConfig(std::move(video));
+
+    AudioConfig audio;
+    audio.stream_label = "alice-audio";
+    audio.mode = AudioConfig::Mode::kFile;
+    audio.input_file_name =
+        test::ResourcePath("pc_quality_smoke_test_alice_source", "wav");
+    audio.sampling_frequency_in_hz = 48000;
+    audio.sync_group = "alice-media";
+    alice->SetAudioConfig(std::move(audio));
+    alice->SetVideoCodecs({VideoCodecConfig(cricket::kH264CodecName)});
+    alice->SetVideoEncoderFactory(webrtc::test::CreateObjCEncoderFactory());
+    alice->SetVideoDecoderFactory(webrtc::test::CreateObjCDecoderFactory());
+  });
+  AddPeer(network_links.second, [](PeerConfigurer* charlie) {
+    charlie->SetName("charlie");
+    VideoConfig video(160, 120, 15);
+    video.stream_label = "charlie-video";
+    video.temporal_layers_count = 2;
+    charlie->AddVideoConfig(std::move(video));
+
+    AudioConfig audio;
+    audio.stream_label = "charlie-audio";
+    audio.mode = AudioConfig::Mode::kFile;
+    audio.input_file_name =
+        test::ResourcePath("pc_quality_smoke_test_bob_source", "wav");
+    charlie->SetAudioConfig(std::move(audio));
+    charlie->SetVideoCodecs({VideoCodecConfig(cricket::kH264CodecName)});
+    charlie->SetVideoEncoderFactory(webrtc::test::CreateObjCEncoderFactory());
+    charlie->SetVideoDecoderFactory(webrtc::test::CreateObjCDecoderFactory());
+  });
+
+  fixture()->AddQualityMetricsReporter(
+      std::make_unique<StatsBasedNetworkQualityMetricsReporter>(
+          std::map<std::string, std::vector<EmulatedEndpoint*>>(
+              {{"alice", network_links.first->endpoints()},
+               {"charlie", network_links.second->endpoints()}}),
+          network_emulation()));
+  RunParams run_params(TimeDelta::Seconds(2));
+  run_params.enable_flex_fec_support = true;
+  RunAndCheckEachVideoStreamReceivedFrames(run_params);
+}
+#endif
+
 // IOS debug builds can be quite slow, disabling to avoid issues with timeouts.
 #if defined(WEBRTC_IOS) && defined(WEBRTC_ARCH_ARM64) && !defined(NDEBUG)
 #define MAYBE_ChangeNetworkConditions DISABLED_ChangeNetworkConditions